Identifying secondary AML (sAML)
Therapy-related AML (t-AML)1
WHO defines t-AML as AML that arises from prior cytotoxic therapy or ionizing radiotherapy for an unrelated disease2,3
Cytotoxic therapies associated with development of t-AML3-7,a:
aAntimetabolites, antimicrotubule agents, growth factors, and immunomodulators have also been implicated in t-AML.3
t-AML patient caseb
Name
Mary
Age
60
Diagnosis
t-AML
Prior therapy
Radiotherapy and an R-CVP regimen for follicular lymphoma
bThe information provided is based on a hypothetical patient case.